Looking to escape the hustle and bustle of city life? The Central Appalachian Highlands offer a treasure trove of secluded towns where time seems to slow down and nature takes center stage. Nestled among rolling hills, dense forests, and winding rivers, these hidden gems provide the perfect backdrop for a serene getaway or a peaceful place to call home. From historic coal towns to mountain retreats with natural hot springs, each locale boasts its own unique charm and allure. Join us as we count down ten of the most secluded towns in this breathtaking region, revealing their secrets and why they’re worth the journey.
10. Talcott, West Virginia: The Quiet Hamlet of the John Henry Legend

Talcott, with a population of just a few hundred residents, is a tranquil riverside community steeped in folklore and history. Best known as the home of the legendary steel-driving man, John Henry, visitors can explore the John Henry Historical Park, which celebrates the town’s rich railroad heritage. Outdoor enthusiasts enjoy fishing, kayaking, and canoeing along the scenic Greenbrier River that flows gently beside the town. With no major industries dominating the landscape, Talcott maintains its peaceful atmosphere, free from the noise and rush of urban centers. The town’s seclusion is enhanced by its rural setting, surrounded by rolling hills and dense woodlands, making it a perfect retreat for those seeking solitude. Life in Talcott moves at a slower pace, allowing residents and visitors alike to appreciate the simple pleasures of small-town living.
Where is Talcott?

Located in Summers County in southeastern West Virginia, Talcott sits quietly along the Greenbrier River, nestled amid the picturesque Appalachian Mountains. Its seclusion stems from its remote setting away from major highways and cities, offering a peaceful respite from the outside world. To reach Talcott, travelers can take Interstate 64 to exit 139, then follow smaller state routes through scenic countryside to arrive at this hidden gem. The town’s distance from urban centers and limited accessibility contribute to its serene atmosphere, making it a haven for those looking to escape the daily grind.
9. Harlan, Kentucky: A Cultural Gem in the Appalachian Heartland

Harlan, home to approximately 1,700 residents, is a small town rich in coal mining heritage and deeply rooted in Appalachian culture. Visitors can delve into the area’s history at the Kentucky Coal Museum or embark on the Portal 31 Underground Tour to experience a mine firsthand. Outdoor activities abound with nearby attractions like Kingdom Come State Park, offering hiking trails, rock formations, and stunning overlooks. The town’s economy has historically centered around coal mining, which shaped its identity and community spirit. Harlan’s seclusion comes from its location deep within the Appalachian Mountains, surrounded by rugged terrain that has preserved its authentic charm. This isolation has allowed Harlan to maintain its cultural traditions, offering a unique glimpse into the soulful history of the region.
Where is Harlan?

Nestled in the heart of southeastern Kentucky, Harlan is situated in Harlan County, bordered by the Appalachian Mountains on all sides. Its secluded nature is due to the mountainous landscape that envelops the town, making it a hidden enclave away from bustling urban centers. To reach Harlan, travelers often traverse winding mountain roads, such as U.S. Route 421, which offer breathtaking views but require a dedicated journey. This remote location not only enhances Harlan’s tranquil atmosphere but also preserves the rich cultural heritage that makes it a standout destination in the Appalachian Highlands.
8. Pembroke, Virginia: The Riverside Town with Cascading Falls

With a population of just over 1,100 residents, Pembroke is a charming town set along the banks of the New River. It’s perhaps best known for the nearby Cascades Waterfall, a stunning 66-foot waterfall surrounded by lush forests, accessible by a scenic hiking trail that draws nature lovers from all around. The town offers a peaceful environment, where activities like fishing, kayaking, and leisurely walks along the river are part of everyday life. Pembroke doesn’t have major industries, which contributes to its small-town feel and tight-knit community. Its seclusion is amplified by the enveloping mountains and forests of the Appalachian landscape, providing a serene backdrop for those seeking tranquility. The lack of urban development allows Pembroke to maintain its pristine natural beauty and relaxed pace of life.
Where is Pembroke?

Pembroke is located in Giles County in southwestern Virginia, nestled in the Appalachian Mountains near the West Virginia border. The town’s secluded nature is due to its setting amid dense forests and mountainous terrain, away from major highways and bustling cities. To get to Pembroke, visitors often take U.S. Route 460, which winds through the picturesque countryside and provides glimpses of the area’s natural splendor. This remote location makes Pembroke an ideal escape for those looking to immerse themselves in nature and experience the serene ambiance of the Central Appalachian Highlands.
7. Unicoi, Tennessee: A Quiet Mountain Town Surrounded by Natural Beauty

Unicoi, with a population of approximately 3,600 residents, is a tranquil mountain town nestled in the northeastern corner of Tennessee. Surrounded by the expansive Cherokee National Forest, it serves as a gateway to outdoor adventures, including hiking the Appalachian Trail, exploring waterfalls, and camping under the stars. The town is home to the annual Unicoi County Apple Festival, celebrating the local community and traditions. With few major industries, Unicoi retains its small-town charm, focusing on local businesses and outdoor tourism. Its secluded atmosphere is a result of its mountainous surroundings and the dense forests that envelop the area, providing a peaceful retreat from the bustle of city life. Residents and visitors alike relish the opportunity to connect with nature in this serene setting.
Where is Unicoi?

Situated in northeastern Tennessee, Unicoi lies just south of Johnson City and is bordered by the Cherokee National Forest to the east. The town’s seclusion stems from its location within the Appalachian Mountains, away from major metropolitan areas and thoroughfares. Access to Unicoi is mainly via Interstate 26, which connects it to nearby cities while still preserving its remote feel. The surrounding natural beauty and limited urban development make Unicoi an ideal spot for those seeking solace amidst the wonders of the Appalachian wilderness.
6. Elkhorn City, Kentucky: Gateway to the Grand Canyon of the South

Elkhorn City, with its close-knit community of nearly 1,000 residents, proudly sits as the gateway to Breaks Interstate Park, famously dubbed the “Grand Canyon of the South.” This small town offers access to breathtaking gorges, sandstone cliffs, and the wild waters of the Russell Fork River, perfect for whitewater rafting and kayaking enthusiasts. Outdoor adventures abound with numerous hiking trails and opportunities for rock climbing and bird watching. Historically, Elkhorn City served as a railroad and coal town, but today, it embraces tourism geared toward nature lovers and thrill-seekers. The town’s seclusion is accentuated by its rugged surroundings and position off the beaten path, making it a hidden gem for those looking to explore unspoiled natural landscapes. Its quiet streets and friendly locals add to the charm of this secluded Appalachian town.
Where is Elkhorn City?

Located in eastern Kentucky near the Virginia state line, Elkhorn City is nestled in Pike County amid the Appalachian Mountains. Its secluded nature arises from its remote location, surrounded by dense forests and steep terrain, far from major highways and urban centers. Access to Elkhorn City is primarily via U.S. Route 460 or Kentucky Route 80, which wind through mountainous landscapes offering scenic vistas. The town’s isolation provides a peaceful retreat and makes it a prime destination for outdoor enthusiasts seeking to explore the less-traveled corners of the Central Appalachian Highlands.
5. Cumberland Gap, Tennessee: The Historic Passageway Through the Mountains

Cumberland Gap, home to around 500 residents, is a quaint town steeped in history and natural beauty. It’s famously known as the “Gateway to the West” for early American pioneers traversing through the Cumberland Gap in the Appalachian Mountains. Today, visitors can explore the Cumberland Gap National Historical Park, which offers historical exhibits, well-preserved hiking trails, and panoramic views from the Pinnacle Overlook. The town maintains a peaceful atmosphere with small local businesses catering to tourists and history buffs. Its seclusion is rooted in its mountainous surroundings and the preservation of its historical landscapes, providing a unique blend of serenity and heritage. The lack of large industries and urban development allows Cumberland Gap to retain its charming, small-town feel.
Where is Cumberland Gap?

Situated at the junction where Tennessee meets Kentucky and Virginia, Cumberland Gap lies in Claiborne County in northeastern Tennessee. The town’s secluded ambiance is due in part to the encompassing Appalachian Mountains and its location away from major urban centers. Access is available via U.S. Route 25E, which passes through the historic Cumberland Gap Tunnel, connecting travelers to this historic passageway. The remote setting and rich historical context make Cumberland Gap a captivating destination for those eager to step back in time and immerse themselves in the tranquil beauty of the Appalachians.
4. Damascus, Virginia: The Trail Town at the Heart of Adventure

With a population of approximately 800 residents, Damascus has earned the nickname “Trail Town USA” thanks to the convergence of seven major trails, including the famous Appalachian Trail and the Virginia Creeper Trail. This charming town is a haven for hikers, cyclists, and outdoor enthusiasts, offering endless opportunities for adventure amid the breathtaking Appalachian scenery. Each year, Damascus hosts Trail Days, a popular festival celebrating hiking culture and drawing visitors from around the world. The local economy thrives on tourism, with businesses catering to the needs of trail-goers and nature lovers. Damascus’s seclusion is underscored by its position deep within the mountains, where the pace of life is dictated by the rhythms of nature. The absence of large-scale industries and urban sprawl allows Damascus to preserve its quaint, welcoming atmosphere.
Where is Damascus?

Located in southwestern Virginia’s Washington County, Damascus sits close to the Tennessee border amid the rolling peaks of the Appalachian Mountains. Its secluded setting is due to the surrounding mountainous terrain and its distance from major highways and cities. Access to Damascus is mainly through U.S. Route 58, which meanders through the scenic countryside and brings travelers to this outdoor paradise. The town’s remote location enhances its appeal as a peaceful retreat and a central hub for exploring the natural wonders of the Appalachians.
3. Hot Springs, North Carolina: A Serene Retreat with Natural Mineral Baths

Hot Springs, with a close-knit community of around 560 residents, is a tranquil haven famed for its natural hot mineral springs that have attracted visitors for centuries. Nestled along the French Broad River and intersected by the Appalachian Trail, the town offers a unique blend of relaxation and adventure. Visitors can soak in the healing waters at the Hot Springs Resort and Spa, explore scenic hiking trails, or enjoy white-water rafting and fishing in the river. Tourism is the lifeblood of Hot Springs, with local businesses catering to wellness seekers and outdoor enthusiasts. The town’s secluded setting, surrounded by the Pisgah National Forest, enhances its peaceful ambiance, making it an ideal spot to unwind and reconnect with nature. The absence of urban distractions allows Hot Springs to maintain its serene atmosphere and small-town charm.
Where is Hot Springs?

Situated in Madison County in western North Carolina, Hot Springs lies near the Tennessee border, cradled by the Blue Ridge Mountains. Its seclusion is a result of its encirclement by national forest land and limited access roads. Travelers can reach Hot Springs via U.S. Route 25/70, which threads through the mountains and brings visitors to this secluded retreat. The town’s remote location not only preserves its natural beauty but also provides a sanctuary for those seeking solace amidst the tranquil landscapes of the Central Appalachian Highlands.
2. Matewan, West Virginia: A Historic Coal Town Nestled in the Hills

Matewan is a small town of about 500 residents, steeped in the rich history of the coal miners’ labor movement of the early 20th century. Known for the Matewan Massacre of 1920, a significant event in the fight for miners’ rights, the town offers historical tours and museums like the Matewan Depot Replica Museum to immerse visitors in its storied past. Nestled in the Appalachian hills, Matewan provides opportunities for outdoor activities such as hiking and exploring the scenic Tug Fork River. While coal mining once dominated the local economy, today, the town leans toward heritage tourism, preserving its history for future generations. Matewan’s secluded nature is due to its deep roots in the rugged terrain, with the surrounding mountains fostering a tight-knit community. The absence of large-scale urban development allows the town to maintain its historic charm and peaceful environment.
Where is Matewan?

Located in Mingo County in southwestern West Virginia, Matewan sits along the Tug Fork River near the Kentucky border. The town’s seclusion comes from its position nestled in the hills of the Appalachians, away from major highways and urban centers. Access is primarily via West Virginia Route 49 or U.S. Route 119, which wind through the mountainous landscape. This remote setting has helped Matewan preserve its historical significance and tranquil atmosphere, making it a poignant destination for those interested in American labor history and Appalachian culture.
1. Burkes Garden, Virginia: The Pristine Valley Hidden Within a Mountain Ring

Burkes Garden, often referred to as “God’s Thumbprint,” is a unique and secluded valley community with a population of just a few hundred residents. Completely encircled by a mountainous ridge, this pristine valley boasts fertile farmland and picturesque landscapes that have remained largely untouched by modern development. Visitors can enjoy leisurely bike rides along the scenic country roads, explore historic homes and churches, or simply take in the serene beauty of the Appalachian highlands. Agriculture remains the primary industry, with the valley’s rich soil supporting farming traditions that date back centuries. Burkes Garden’s seclusion is inherent in its geography, as the mountain ring creates a natural barrier to the outside world. This isolation has preserved the tranquil way of life for which the community is known.
Where is Burkes Garden?

Situated in Tazewell County in southwestern Virginia, Burkes Garden lies east of the town of Tazewell and is nestled within the highest valley in Virginia. The area’s seclusion arises from its unique topographyโa basin entirely surrounded by Garden Mountain, accessible only by a single road winding over the ridge. To reach Burkes Garden, travelers must navigate State Route 623, which ascends and descends through breathtaking mountain scenery. The valley’s remote location and natural enclosure make it one of the most isolated and serene spots in the Central Appalachian Highlands, offering a rare glimpse into an untouched rural landscape.