
If you’re yearning for a peaceful escape, Southeast Missouri is home to some of the most secluded towns that offer tranquility away from the bustling city life. I’ve discovered that these hidden gems are perfect for anyone seeking solitude amidst nature’s embrace.
From dense forests to rolling hills, each town provides a unique retreat where privacy and serenity are paramount. Whether you’re looking to relocate or simply want a quiet vacation spot, these towns boast expansive landscapes, minimal population, and a pace of life that lets you breathe easy.
Join me as we explore these ten secluded towns that make Southeast Missouri a haven for those wanting to get away from it all.
10. Millersville: A Quiet Community Near the River

Millersville is a small, unincorporated community with a population of around 200 residents. I love how the town offers a peaceful atmosphere, surrounded by large properties that provide plenty of privacy. Outdoor enthusiasts can enjoy nearby natural features like the Whitewater River, perfect for fishing and canoeing.
The main industries here are agriculture and small local businesses, contributing to its quaint charm. Millersville’s secluded setting, with its expansive farmland and distance from urban centers, makes it an ideal spot for those seeking peace and privacy.
Where is Millersville?

Located in Cape Girardeau County, Millersville sits approximately 15 miles northwest of Cape Girardeau city. Its seclusion is enhanced by the surrounding rural landscapes and limited major roadways passing through the area.
To get there, you can take Route 72 west from Cape Girardeau and then head north on Route B, winding through scenic countryside. I’ve found that the journey itself, through the rolling hills and farmlands, adds to the sense of escaping into a tranquil retreat.
9. Higdon: Hidden in Madison County’s Wilderness

Higdon is an unincorporated community with a sparse population that offers a true escape into wilderness. Nestled amidst dense forests and natural surroundings, it’s a place where you can genuinely disconnect from urban life.
There aren’t many commercial activities, but the area is perfect for hiking, wildlife observation, and enjoying the serenity of nature. The lack of major industries keeps the area pristine and undisturbed. What makes Higdon secluded is its minimal development and the vast stretches of untouched land that envelop it.
Where is Higdon?

You’ll find Higdon in Madison County, situated in the southeastern part of Missouri. It’s tucked away off State Highway J, surrounded by the expanses of the Mark Twain National Forest. Getting there involves navigating rural roads that wind through the forests, which to me, feels like uncovering a secret hideaway.
The community’s remote location and the natural barriers provided by the forests contribute to its seclusion, making it a perfect spot for those wanting to immerse themselves in nature.
8. Patton: Peaceful Countryside Living

Patton is a small town with a population of about 350 people, offering a tranquil rural lifestyle. The expansive landscapes and rolling farmlands provide a picturesque setting that’s hard to find elsewhere. While there aren’t many tourist attractions, the simplicity of life here is its main draw.
Agriculture is the primary industry, with many residents engaged in farming and related activities. Patton’s low population density and the vast open spaces make it an ideal place for those who value peace and quiet.
Where is Patton?

Located in Bollinger County, Patton lies at the junction of State Highways 51 and 72. Its location away from major cities contributes to its secluded feel. To reach Patton, you can drive south from Perryville or north from Marble Hill, enjoying the scenic views along the way.
I appreciate how the journey through the countryside sets the tone for the serenity that Patton offers. The town’s distance from urban centers ensures a lifestyle that’s free from the usual hustle and bustle.
7. Gravelton: Seclusion in the Ozark Foothills

Gravelton is a tiny, unincorporated community nestled in the foothills of the Ozarks. With a population that’s just a handful, it’s perfect for those desiring a truly secluded dwelling. The area is surrounded by forests and hills, providing ample opportunities for hiking and exploring the natural terrain.
There are no significant industries, which helps maintain its untouched environment. Gravelton’s remote location and the lack of commercial development make it a haven for solitude seekers like me.
Where is Gravelton?

Situated in Wayne County, Gravelton is found along Route 34, west of Jackson. The community is enveloped by the vastness of the Ozark forests, enhancing its sense of isolation. Getting there involves driving through winding roads that cut through the hills and forests, which I find incredibly serene.
The natural barriers formed by the landscape contribute to its seclusion, making Gravelton a perfect escape from the modern world’s demands.
6. Gipsy: Rural Charm and Privacy

Gipsy is a rural community with an estimated population of around 100 residents. The town is characterized by its spacious lot sizes and rustic setting, allowing residents to connect deeply with nature. While amenities are minimal, the area offers plenty of outdoor activities like fishing, hunting, and horseback riding.
Agriculture plays a significant role in the local economy. Gipsy’s privacy stems from its remote location and the vast acreage that separates neighbors, offering an ideal retreat for those valuing solitude.
Where is Gipsy?

Gipsy is located in Bollinger County, along Route ZZ, north of Marble Hill. The community is off the beaten path, with surrounding woodlands and farmland enhancing its secluded atmosphere.
To reach Gipsy, you navigate rural roads that are less traveled, something I find adds to its charm. The lack of through traffic and its distance from larger towns bolster Gipsy’s status as a private and peaceful community.
5. Cascade: Gateway to Peaceful Wilderness

Cascade is a small community with a population of fewer than 100 people. It’s known for its proximity to natural landscapes like the Castor River and nearby conservation areas. Residents and visitors can enjoy activities such as fishing, canoeing, and exploring the serene wilderness.
There are few industries, ensuring minimal human impact on the environment. The low housing density and abundance of natural surroundings make Cascade a secluded haven that I find truly rejuvenating.
Where is Cascade?

Found in Wayne County, Cascade is situated along State Highway M, southeast of Silva. Its location near the Castor River and surrounding forests adds to its peaceful ambiance. Accessing Cascade involves traversing rural highways that meander through the Ozark foothills.
The remoteness of the area, coupled with the natural beauty, makes getting there as much a part of the experience as the destination itself. The sparse population and limited development contribute significantly to its seclusion.
4. Lowndes: Embraced by Nature’s Tranquility

Lowndes is an unincorporated community with a small population that offers a serene environment far from city life. The area is abundant with undeveloped land, including forests and streams, providing a tranquil backdrop for residents. There are opportunities for outdoor activities like hiking and wildlife watching.
With no major industries, the community maintains its quiet charm. I appreciate how Lowndes’ remote location ensures a peaceful lifestyle, free from the noise and stress of urban areas.
Where is Lowndes?

Located in Wayne County, Lowndes can be found along State Highway E, northeast of Greenville. The town’s seclusion is due in part to its position amidst the natural landscapes of Southeast Missouri.
Getting to Lowndes requires a drive through scenic rural roads, which I find enhances the sense of escape. The isolation provided by the surrounding wilderness makes it an ideal spot for those looking to disconnect and enjoy nature’s tranquility.
3. Clubb: Off-the-Grid Living

Clubb is a tiny community where off-the-grid living is not just a concept but a way of life. With a minimal population, it offers expansive properties, perfect for anyone wanting space and privacy. The area is rich in natural beauty, including forests and streams, ideal for outdoor enthusiasts like me.
There are no significant industries, which helps preserve its untouched environment. Clubb’s seclusion comes from its remote location and the minimal population density that allows for a truly private lifestyle.
Where is Clubb?

Situated in Wayne County, Clubb is accessible via rural routes off State Highway 34. The community is nestled deep within the wooded areas of the region, enhancing its secluded feel. The journey to Clubb involves driving through scenic landscapes that seem untouched by time.
The absence of major roads and towns nearby contributes to its off-the-grid status, making it an excellent choice for those seeking to live close to nature.
2. Dongola: Hidden Serenity in Wayne County

Dongola is an unincorporated community that epitomizes peaceful living. With a small population, it sits amid rolling hills and natural barriers, making it ideal for those seeking solitude. While there aren’t many attractions, the simplicity of the surroundings is perfect for reflection and relaxation.
Agriculture is prevalent, and the community sustains itself through local farming practices. I find that Dongola’s secluded nature and serene environment make it a quiet haven away from the hustle.
Where is Dongola?

Located in Wayne County, Dongola is found along State Highway 51, north of Puxico. The town’s seclusion is enhanced by the surrounding landscapes of forests and hills. To get there, you’d drive through winding roads that showcase Southeast Missouri’s natural beauty.
The lack of nearby urban centers and the enclosing natural features make Dongola feel like a world apart, offering a peaceful retreat for its residents.
1. Arab: A Quiet Retreat in Bollinger County

Arab is a tiny community with a population of around 50 people, offering one of the most secluded living experiences in Southeast Missouri. Surrounded by dense forests and large acreages, residents here enjoy unparalleled privacy.
The area is perfect for nature lovers, with opportunities for hunting, hiking, and simply enjoying the tranquility of the woods. There are no major industries, which keeps the area quiet and free from industrial noise.
I admire Arab for its ability to provide a genuine retreat away from the urban hustle, making it an ideal spot for those wanting to embrace solitude.
Where is Arab?

You’ll find Arab in Bollinger County, located along State Highway C, southwest of Zalma. Its remote location, enveloped by vast forested areas, contributes to its secluded atmosphere.
Getting to Arab involves traveling through rural roads that are less frequented, enhancing the feeling of stepping into a hidden sanctuary. The community’s isolation is a significant draw for those like me, who value peace and a strong connection with nature.